Research shows that normalization of low testosterone levels with the use of testosterone replacement therapy (TRT) helped decrease risk of heart attack, stroke and premature mortality. After performing studies on a group of older men without history of heart attack or stroke and who had below-average testosterone levels were given TRT. There were 47% fewer deaths among the group with normalized testosterone levels compared to men whose hormone levels failed to normalize, and there were 56% fewer deaths than those who did not receive TRT.  Results show that testosterone carries anti-inflammatory and other beneficial effects and that normalization of testosterone levels using TRT is linked to lower mortality, fewer heart attacks and strokes if the dose is adequate to normalize the testosterone levels.